Worth adding you should check tyre pressures when cold to ensure accuracy.I get about 36mpg (LWB 150 DSG loaded camper) on long runs on crossclimates but then I'm running a much less extreme tyre size than you (235/55/17 @ 48psi).
Tread pattern will have an effect on MPG and that will be shown on the EU label as a rating - interesting to see what the rating for both tyres says. But lots of other things will affect mpg too - heated mirrors, AC etc, stiffness of tyre walls which will vary with temperature, pressure, driving style (you may have more confidence with your new tyres and hoon the van round quicker without even realising.